IRC log of dse1 on 2007-04-13
Timestamps are in UTC.
- 12:38:10 [RRSAgent]
- RRSAgent has joined #dse1
- 12:38:10 [RRSAgent]
- logging to http://www.w3.org/2007/04/13-dse1-irc
- 12:38:21 [eneumann]
- rrsagent, set log world-visible
- 12:38:34 [eneumann]
- scenario draft: http://esw.w3.org/topic/HCLSIG/Drug_Safety_and_Efficacy/Scenarios/Genetic_Diagnostic_CT#preview
- 12:39:00 [mswietek]
- mswietek has joined #DSE1
- 12:39:10 [sdobson]
- linkage analysis for colon cancer contributors, would this be a whole genome scan or specific genes
- 12:40:21 [sdobson]
- probably do specific genotyping for cyp alleles
- 12:41:41 [sdobson]
- I should introduce Mike Swietek. He works at Pfizer and is in the office with me at the moment.
- 12:41:56 [sdobson]
- I'm just getting him familiar with the Zakim irc
- 12:42:26 [mswietek]
- mswietek has joined #DSE1
- 12:42:30 [eneumann]
- says: Hi mike
- 12:42:43 [mswietek]
- Hello Eric, my web browser crashed
- 12:43:02 [eneumann]
- this should help... http://www.w3.org/2002/01/UsingZakim
- 12:43:25 [mswietek]
- Thanks
- 12:43:52 [eneumann]
- also if you're a tekkie... http://www.w3.org/2001/12/zakim-irc-bot.html
- 12:44:59 [mswietek]
- Thanks again
- 12:45:06 [eneumann]
- for the GeneChip, I assumed looking specifically at Cyp alleles rather than whole genome-- should be more practical?
- 12:45:36 [sdobson]
- Probably but by the time we get to Phase 11B we're pretty confident we know what metabolises our compound
- 12:45:55 [sdobson]
- so we'd go with a specfic genotype test more accurate than the gene chip
- 12:46:20 [sdobson]
- we'd use the genechip for exploratory work to look at other possible snps in teh pathway
- 12:46:44 [sdobson]
- or to subset populations based on safety information, I expect
- 12:48:17 [eneumann]
- What is the name of the Affy-Roche CYP diagnostic chip?
- 12:48:56 [sdobson]
- amplichip I think
- 12:49:08 [sdobson]
- don't think we've used it
- 12:49:48 [mswietek]
- Amplichip CYP 450
- 12:50:21 [eneumann]
- thanks... Kerstin is calling me on my phone-- should be interesting!
- 12:50:43 [sdobson]
- If it's just Kerstin, you and us I can send out a conference number for us
- 12:51:58 [eneumann]
- That's all we need-- Bo can't make it.-- thanks!
- 12:54:49 [sdobson]
- Numbers have been mailed to you talk in a minute
- 13:54:43 [eneumann]
- Action: add CT data re-use steph #6
- 13:55:25 [eneumann]
- action: distinguish geno screening from gene analysis
- 13:55:40 [eneumann]
- set up TC with Stan Huff
- 13:55:54 [eneumann]
- action: set up TC with Stan Huff
- 13:56:15 [eneumann]
- action: put together DSE paper schedule
- 13:56:24 [eneumann]
- rrsagent, draft minutes
- 13:56:24 [RRSAgent]
- I have made the request to generate http://www.w3.org/2007/04/13-dse1-minutes.html eneumann
- 13:56:34 [eneumann]
- bye rrsagent
- 13:56:39 [eneumann]
- rrsagent, bye
- 13:56:39 [RRSAgent]
- I see 4 open action items saved in http://www.w3.org/2007/04/13-dse1-actions.rdf :
- 13:56:39 [RRSAgent]
- ACTION: add CT data re-use steph #6 [1]
- 13:56:39 [RRSAgent]
- recorded in http://www.w3.org/2007/04/13-dse1-irc#T13-54-43
- 13:56:39 [RRSAgent]
- ACTION: distinguish geno screening from gene analysis [2]
- 13:56:39 [RRSAgent]
- recorded in http://www.w3.org/2007/04/13-dse1-irc#T13-55-25
- 13:56:39 [RRSAgent]
- ACTION: set up TC with Stan Huff [3]
- 13:56:39 [RRSAgent]
- recorded in http://www.w3.org/2007/04/13-dse1-irc#T13-55-54
- 13:56:39 [RRSAgent]
- ACTION: put together DSE paper schedule [4]
- 13:56:39 [RRSAgent]
- recorded in http://www.w3.org/2007/04/13-dse1-irc#T13-56-15