Clinical Decision Support: Execution and Knowledge Propagation Safety Surveillance and Innovation Adoption

• Imagine a new therapeutic with the possible guideline:

• • • All Patients with Obesity should be on a New Appetite Suppressant Drug unless there is a “contraindication”
    • All patients on this new obesity drug should be followed for liver function test abnormalities every 6 months

• Must define who has Obesity and Contraindication State

• • • available data would include problems, documentation (ie BMI > 30), active medications (other appetite suppressants or diet orders), test results (basal metabolic rate, LFTs), and last resort, claims),

• Must maintain these state definitions in a common way (ontology management) instead of replicating these in rules, templates, reporting environments, etc.

• Must be able to adapt protocols rapidly in responses to discovery of new knowledge (knowledge event management)