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Drug Safety Determination
Notes:
Once you can integrate data from bench to bedside there will be
tremendous benefits.
This slide shows an example of a query that spans many silos in LS
& HC, enabling people to see the complete picture regarding
drug safety.
The drug discovery and development process is typically a gated
process, so if a compound is good enough at a particular stage it
gets thrown over the fence to the next department. Companies don’t
look at the complete picture, which would prove to be very
valuable.
The query ends with ‘and if…..’. If ontologies were used, it would
also be possible to state that a skin rash, is an inflammation of
the skin. If a different physician reported that someone else had
dermatitis, then this would also be considered to be inflammation
of the skin. So it becomes possible to integrate all data and see
the whole picture.